It might be remembered for the plexiglass, or for the relative tameness, or perhaps not at all given the chaos back in Washington and the frenetic pace of the campaign as a whole.

Or it might be remembered for searing attacks not just on opposing plans but on entirely different portrayals of the past and visions of the near future, amid a pandemic that seldom has felt more urgent.

At a moment of intense focus on the health of a president, and with two historically old candidates topping the ticket, the running mates engaged in an emotional and highly personal debate – just one lacking the insults and outsized personalities of President Donald Trump and former Vice President Joe Biden.

[Read more of ABC News Political Director Rick Klein's analysis](43806451takeover2headlineshed>).

The vice presidential candidates for president faced off on Wednesday for their first and only debate, giving Americans a much more substantive look at the ticket — though often not the substance that they were prompted for.

The candidates repeatedly dodged the questions from moderator Susan Page, remaining focused on one thing: correcting the wrongs of last week’s debate.

Here are the key takeaways.

--ABC News' Cheyenne Haslett and Meg Cunningham

PENCE'S CLAIM: "President Trump and I are fighting every day in courthouses to prevent Joe Biden and Kamala Harris from changing the rules and creating this universal mail-in voting that will create a massive opportunity for voter fraud."

FACT CHECK: Pence echoed Trump's attempts to cast doubt on the widespread embrace of vote-by-mail across the country this election by suggesting that universal mail-in voting could lead to massive fraud.

That is historically not true.

Kim Wyman, the Republican secretary of state in Washington -- a state that adopted statewide mail voting in 2011 -- told The New York Times in June that while any voting method could potentially be susceptible to fraud, in her experience as the chief elections official in the state, fraud with mail ballots is low.

"How do you respond to someone that makes an allegation that there's rampant fraud?" she said. "You show them all the security measures that are in place to prevent it and detect it if it does happen."

Ben Ginsberg, a Republican election guru who has spent years looking for voter fraud, wrote in a Washington Post op-ed, "Four decades of dedicated investigation have produced only isolated incidents of election fraud."

"These are painful conclusions for me to reach. Before retiring from law practice last month, I spent 38 years in the GOP's legal trenches. I was part of the 1990s redistricting that ended 40 years of Democratic control and brought 30 years of GOP successes in Congress and state legislatures. I played a central role in the 2000 Florida recount and several dozen Senate, House and state contests," he wrote. "The truth is that after decades of looking for illegal voting, there's no proof of widespread fraud."

Tom Ridge, a Republican who previously served as the governor of Pennsylvania and was the nation's first secretary of Homeland Security, previously told ABC News, "There is absolutely no antecedent, no factual basis for (President Donald Trump's) claim of massive fraud in mail voting."

--ABC News; Kendall Karson

PENCE'S CLAIM: "It's probably why Newsweek magazine said that Kamala Harris was the most liberal member of the United States Senate in 2019, more liberal than Bernie Sanders, more liberal than any of the others in the United States Senate."

FACT CHECK: Harris certainly has a very liberal Senate voting record, and an analysis cited by Newsweek in 2019 did find her to be the most liberal in the U.S. Senate.

However, that particular analysis does not consider some important caveats, the founder of the organization who conducted it told ABC News.

, an independent and nonpartisan group, found that Harris was the "most liberal" of her Senate colleagues in a 2019 survey, which compared the number of bipartisan bills a senator co-sponsored to the total number of bills he or she signed onto. Harris had the smallest percent of bipartisan bills in 2019, making her the most-liberal senator by this metric.

Harris certainly has one of the more liberal voting records in the Senate: She has voted to increase gun control and block conservative judicial nominees, for instance.

But there are nuances that the organization's founder, Jonathan Tauberer, said GovTrack's model doesn't account for, like the complexity of Harris' political views, the distinctions between different wings within each major political party, the specific approach Harris might take to achieve her desired outcome, or the unwillingness of Republicans to work with Harris during a presidential year.

--ABC News' Allison Pecorin

In light of President Trump's positive COVID-19 diagnosis and subsequent concerns from Harris' team, the Commission on Presidential Debates agreed to add additional safety precautions to Wednesday's debate at the University of Utah.

Unlike last week's presidential debate, everyone in the audience will be required to wear a face mask or covering and those who don't will be escorted out of the venue.

"They've got to wear a mask, and if they take their mask off they're gonna be escorted out, and I don't care who they are, they'll be escorted out," Frank Fahrenkopf, chairman of the Commission on Presidential Debates, told ABC News.

Harris and Pence will be tested prior to the debate, according to the commission, a change from the presidential debate when campaigns were responsible for testing their candidates and traveling parties.

And the candidates will be separated by more than just the issues -- or at least one of them will be.

After Pence's close proximity to others who have tested positive for COVID-19, the Harris campaign requested plexiglass barriers be used at the debate and the commission agreed -- but the Pence campaign said Tuesday that they never agreed to a plexiglass partition.

A senior administration official in Pence's office told ABC News Tuesday that the CPD decided to publicize the new safety protocols before any formal agreement was made and that the moderator and the Harris campaign can do as they want, "but we do not."

The official said Center for Disease Control and Prevention guidelines recommend plexiglass whenever 6 feet of separation isn't possible, but noted the candidates will be 12-feet apart on stage. The comment fell in line with Pence's chief of staff Marc Short who told The Washington Post Tuesday that plexiglass is "not needed."

Pence's communications director, Katie Miller, who tested positive for COVID-19 in May, also responded to the request in a statement to Axios earlier this week saying, "If Sen. Harris wants to use a fortress around herself, have at it."

Following news that Miller's husband, senior Trump aide Stephen Miller, tested positive for the coronavirus, she reportedly left Utah and a spokesperson declined to comment if Pence would agree to plexiglass.

-ABC News Justin Gomez, Averi Harper and Ben Gittleson